Gene Therapy Market Set for Decade-Long Surge as 100+ Firms Target Rare and Complex Diseases

Gene therapy research and development in a laboratory setting

By 2035, gene therapy could redefine the treatment landscape for diseases once deemed incurable, with over 100 companies racing to commercialize groundbreaking therapies.

The global gene therapy R&D market is projected to expand significantly from 2025 to 2035, driven by advancements in treatments for cancer, rare diseases, cardiovascular disorders, ophthalmic conditions, hematological disorders, neurological diseases, and diabetes mellitus.

Key growth factors include increased investment in innovative therapeutics, regulatory support, precision medicine adoption, clinical pipeline expansion, new vector technologies, and scalable manufacturing processes.

Over 100 companies are actively developing gene therapy candidates across diverse indications, including Bluebird Bio, Biogen, Bristol Myers Squibb, Novartis AG, Replimune, and Spark Therapeutics (subsidiary of Roche), with therapies progressing through preclinical and clinical stages.

Strategic collaborations, licensing agreements, and partnerships among companies are accelerating pipeline development and enabling broader access to gene therapy solutions.

The report highlights transformative potential for treating unmet medical needs, particularly in rare and complex conditions, sustained by innovation in delivery methods, biomarker-driven patient selection, and regulatory approvals in North America, Europe, and Asia-Pacific.

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